i don't think this is a serious political issue, but the fact that harris has gifted it as a talking point to the right is reflective of her low talent as a politician, and why she could have never made it to this point on her own.
this is going to happen; harris is going to say something stupid and it is going to hurt her dramatically, but it's an open question just how badly. not enough people are going to take the bogeyman of a centralized price setting agency seriously (although it would actually be very easy to implement. you'd just need to merge the systems. they're all the same.), but she should really try a little harder to keep her foot out of her mouth.