as we know that the universe is expanding everywhere in all directions at the same time, it follows that calculations about the paths of particles, if precise enough, would need to account for that expansion, as the distance traveled, while perhaps computable, could never be measured with a ruler, as the distance is not static. it would follow that the inability to measure a particle's direction and location simultaneously would be a simple consequence of the fact that the universe is expanding: it would be a fundamental property of space-time. however, it would also follow that you could calculate these properties simultaneously by properly understanding the interaction between matter and space, if you alter your conception of space from one of empty, static neutrality into one of dynamic, active interaction.
any future theory of physics would have to being with a model of geometry that is dynamic.
and, as such, the assumption of locality would need to be more carefully analyzed.
perhaps these higher dimensions of string theory as we understand them are in truth merely a crude way to model the fundamentally dynamic nature of space-time.
and, in the end, perhaps the absurdities of quantum physics are just reducible to relativistic error, in a set of reference frames that we don't currently grasp.