so, why take 100 mg per meal, then?
because vitamin c is cleared by your body within hours - it's the reason these megadoses don't work. pauling didn't understand that because the science wasn't there yet. his argument was not bad, but he assumed that we'd store vitamin c for a while if we took huge amounts of it and we just don't - we process it as we come into contact with it and eliminate it as soon as we're done with it.
so, all that taking a 2000 mg pill of vitamin c is going to actually do is put unnecessary strain on your kidneys. unfortunately.
if we could hack ourselves to actually store and release - or potentially even synthesize - vitamin c, the kinds of things that people like pauling talked about could reassert themselves. we all know that we need vitamin c because we can't produce it, but we might not realize that most animals can make their own c and don't need to consume much at all. your dog can make it's own vitamin c, but your cat can't make it's own taurine. we're similar, but these are differences - and they're genetic.
we could flip the switch:
and, then these megadoses would transport c to the liver, where it would be released.
as it is, we just get rid of it very fast - so replenishment is necessary at regular intervals. so, if you're going to do this, you should take 100 mg 2-3 times daily, rather than a large dose all at once.